MALDI-7090

Identification of biomolecules and study of their structure

The MALDI-7090TM MALDI-TOF mass spectrometer is a representative of a sophisticated new generation of MALDI-TOF mass spectrometers – specially designed for the identification of biomolecules and the study of their structure with high productivity and efficiency, which are provided by a complex of unique Shimadzu technologies in the field of mass spectrometry.

Features

High performance platform MultiPlexTM. Maximize the efficiency of your MALDI-7090 by combining a simultaneous loading device for up to 10 MALDI plates, a 2 kHz ultrafast solid-state UV laser, and the multi-user operation of MALDISolutionTM software. Plates prepared for analysis can be loaded and unloaded from the instrument while measurements are being made. The loading chamber can be operated at atmospheric pressure or can be purged with nitrogen to protect labile samples.

Original design of the ionization source.

  • Wide-aperture ion optics: Focused ion stream; Minimal risk of ionization source contamination; Minimal need for ionization source cleaning and maintenance.
  • Patented ultrafast laser: 2kHz ultrafast solid-state UV laser 355nm, compatible with various matrices and samples; Variable beam focusing from 10 microns to more than 100 microns; Long continuous operation time.
  • Sample visualization in HD quality: State-of-the-art optics for high-resolution sample visualization and crystal-clear images; FullHD (1080p) color image; Controlled variable focus for viewing different surfaces.
  • TrueCleanTM: Patented fully automated laser ion source cleaning system; Highly efficient fast cleaning in offline mode.

High-resolution ion shutter. With the help of a new ion gate, it is possible to separate precursor ions with close nominal masses and, thereby, contamination of MS/MS spectra.

ASDF ion focusing technology. ASDFTM technology provides mass resolution in MS/MS mode up to 10,000 (FWHM).

Fragmentation at high and low energies. The MALDI-7090 implements High Energy Collision Induction Dissociation (HE-CID). The collision energy of precursor ions with inert reagent gas molecules in the collision cell reaches 20 keV. In addition, the use of helium as a reagent gas for HE-CID provides (compared to argon or air) more efficient fragmentation (for example, of peptide side chains). Due to the unique curved-field reflectron, the resulting secondary mass spectra are additionally enriched with peaks of metastable fragment ions formed during fragmentation directly in the time-of-flight mass analyzer (Post Source Decay, PSD). The combination of two precursor ion fragmentation pathways (HE-CID and PSD) provides the highest efficiency of TOF/TOF tandem mass spectrometry and obtaining the most informative mass spectra.